Xenograft Tumor Models

Cell name：

NCI-H446

Other names for the model：

H446、H-446、NCI-446、NCIH446

Cell information：

NCI-H446 cells are derived from human small cell lung cancer cells

Model information：

5X10⁶  NCI-H446 cells per mouse are mixed with Matri-gel and inoculated into right flank region in BALB/c Nude mice.

About 10 days post inoculation, the mice can be grouped, with average tumor volumes at 150-250 m³.

The duration of treatment is about 27 days post grouping (when the tumor volumes in the vehicle group reach 2000 m³).