Xenograft Tumor Models

Cell name：

MCF-7 (Orthotopic)

Other names for the model：

MCF 7、MCF.7、MCF7、Michigan Cancer Foundation-7、ssMCF-7、ssMCF7、MCF7/WT、MCF7-CTRL、IBMF-7

Cell information：

MCF-7 cells are derived from human breast cancer pleural effusion and are ER+, PR+, HER2+/-, and EGFR+ breast cancer cells. Click to view More information.

Model information：

1X10⁷ MCF-7 cells per mouse are mixed with Matri-gel and inoculated into the 3rd mammary fat pad in NOD SCID mice.

About 9 days post inoculation, the mice can be grouped, with average tumor volumes at 150-250 m³.

The duration of treatment is about 28 days post grouping (when the tumor volumes in the vehicle group reach 2000 m³).