Animal models play an important role in drug discovery and development, and the use of animal models in drug discovery has long been established as a reliable method for understanding the efficacy and safety of new drug candidates. Efficacy studies in animal models can help scientists determine the most effective dose and frequency of administration for a drug, as well as the most effective route of administration. Efficacy studies in animal models can also provide insight into the pharmacokinetics,pharmacodynamics and the potential toxicity of a drug. This information can also be used to design clinical trials in humans and to evaluate the safety and efficacy of the drug in humans.