Xenograft Tumor Models

Cell name：

ZR-75-1 (Subcutaneous)

Other names for the model：

Zr-75-1、ZR751、ZR75-1、ZR75.1、ZR75_1

Cell information：

ZR-75-1 cells human breast cancer cells, ER+, HER2-. The cells express high levels of the MUC-1 gene, low levels of Muc-2, but no Muc-3 gene. Click to queryMore information.

Model information：

1X10⁷ ZR-75-1 cells per mouse are mixed with Matri-gel and inoculated into right flank region in NOD SCID mice.

About 29 days post inoculation, the mice can be grouped, with average tumor volumes at 150-250 m³.

The duration of treatment is about 32 days post grouping (when the tumor volumes in the vehicle group reach 2000 m³).