Xenograft Tumor Models

Cell name：

HepG2

Cell information：

HepG2 is one of the most commonly used human liver cancer cell lines. The cells express alpha-fetoprotein, albumin, α-2-macroglobulin, α-1-antitrypsin, transferrin, α-1- Antichymotrypsin, haptoglobin, ceruloplasmin, plasminogen, complement C4, C3 activator, fibrinogen, α-1 acid glycoprotein, α-2-HS-glycoprotein, β-lipoprotein, Retinol-binding protein; expresses the receptor for insulin and insulin-like growth factor IGF II. Click to view More information.

Model information：

5X10⁶  HepG2 cells per mouse are mixed with Matri-gel and inoculated into right flank region in BALB/c Nude mice.

About 10 days post inoculation, the mice can be grouped, with average tumor volumes at 150-250 m³.

The duration of treatment is about 26 days post grouping (when the tumor volumes in the vehicle group reach 2000 m³).