Syngeneic Tumor Models

        Syngeneic transplantation of breast cancer model is a commonly used research method, mainly by inoculating tumor cell lines of the same background into immunocompetent inbred mice. The advantage of this model is that the recipient mice have a complete mouse-derived immune system, have full immune activity, and their immune system is compatible with the syngeneic transplant tumor tissue, which can maximize the simulation of the real-life situation of the tumor microenvironment. 

        In addition, the repeatability and operability of the syngeneic transplantation of breast cancer model are good, suitable for large-scale screening. However, this model also has its limitations, such as the transplanted mouse tissue may not fully represent the complexity of human tumors in clinical situations. Therefore, when choosing to use a syngeneic transplantation of breast cancer model, it is necessary to consider comprehensively based on research goals and needs.