Syngeneic Tumor Models

Cell name：

Hepa1-6

Cell information：

Hepa1-6 cells are derived from liver tumors of C57L/J mice. Unlike other commonly used mouse liver tumor cells, Hepa1-6 cells are derived from spontaneously formed liver tumors rather than tumors induced by compounds.

Model information：

Hepa1-6 can form transplanted tumors after inoculation in C57BL/6.

Reactivity to tumor immune drugs ：

Moderate response to multiple immune checkpoint inhibitors

Application areas：

Pharmacodynamic evaluation of multiple immune checkpoint inhibitors alone and in combination