Monkey PK experiment refers to PK experiments conducted in monkey animal models. In monkey PK experiments, researchers will administer specific doses of drugs to the experimental animals (monkeys) and collect blood or tissue samples at different time points to determine drug concentrations. Based on these data, researchers can calculate the absorption, distribution, metabolism, and excretion parameters of drugs in vivo, and establish pharmacokinetic models.
Due to the high similarity in physiology and metabolism between monkeys and humans, monkey PK experiments are commonly used for preclinical drug safety evaluation and pharmacokinetic studies. These experiments can help researchers better understand the behavior of drugs in vivo and provide important evidence for preclinical drug development. In addition, monkey PK experiments can also provide reference for human clinical trials.
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