PBMC-humanized Xenograft Models

Cell name：

A375

Cell information：

A375 cells are derived from human malignant melanoma cells. Express immune checkpoint proteins such as PD-L1, PD-L2, OX40L.

Model information：

Subcutaneous inoculation, with mouse strains NOG and NOG-dko, requires the addition of matrix during inoculation. On the day of vaccination, 2.0 * 10 ^ 6 PBMC cells were injected into the tail vein.