PBMC-humanized Xenograft Models

Cell name：

Jeko-1

Cell information：

JeKo-1 cells are derived from human mantle cell lymphoma cells. JeKo-1 cells are Epstein-Barr virus negative and express a B-cell phenotype of IgM. The cells express CD3-, CD5+, CD10+, CD19+, and overexpress cyclin D1, Bcl-2, c-Myc and Rb proteins. Click to view More information.

Model information：

5X10⁶  Jeko-1 cells per mouse are mixed with Matri-gel and inoculated in NOG or NOG-dko mice. On the day of inoculation, 2X10⁶ PBMC was injected via tail vein injection.